MHRA approves tisotumab vedotin for the treatment of cervical cancer

The Medicines and Healthcare products Regulatory Agency (MHRA) has today, 2 December 2025, approved tisotumab vedotin (Tivdak) used for the treatment of adults with cervical cancer that has come back or spread. It is used if the disease worsened after previous anti-cancer treatment. Tisotumab vedotin is administered via an intravenous infusion (drip) into the vein over 30 minutes once every three weeks. Julian Beach, Interim Executive Director of Healthcare Quality and Access […]
Recruitment for IT Operations Engineer (Infrastructure & Network Lead)

IT Operations Engineer (Infrastructure & Network Lead) who will lead the team responsible for the management of the VMD’s IT Infrastructure and Networks. Source link
Professor Patricia Thornley appointed as new DfT Chief Scientific Adviser

new chief scientific adviser appointed, reinforcing our leadership in science at a national level she brings extensive expertise across sustainable energy and clean transport, which will help shape evidence‑based policy and advance the UK’s transition to net zero her role will be central to ensuring that excellent science advice sits at the heart of decision‑making and strengthens coordination […]
Deputy Prime Minister to Announce ‘Swift and Fair Justice’

Bold modernisation of the criminal courts to put victims first and restore public confidence in the system More than half a billion investment to support victims and witnesses throughout justice process Record Crown Court sitting days to bear down on the backlog Victims will be put front and centre of the justice system as the […]
Birmingham City Council: Ministerial response to Commissioners’ third report

Ministerial response from the Minister of State for Local Government and Homelessness, Alison McGovern MP, to Tony McArdle OBE, Lead Commissioner at Birmingham City Council. Source link
Homes England awards £23 million infrastructure grant in latest step towards unlocking wide-scale regeneration and thousands of new homes in London

Homes England has awarded a £23 million grant to Transport for London (TfL) as part of the Agency’s ongoing support to help transform two major brownfield sites into thriving communities at Thamesmead Waterfront and Beckton Riverside. The grant will fund a new bus link to connect new housing and enhance existing bus corridors linking Thamesmead […]
PM call with President Zelenskyy of Ukraine and President Macron of France: 1 December 2025

The Prime Minister spoke to President of Ukraine, Volodymyr Zelenskyy, and the President of France, Emmanuel Macron, this afternoon. Source link
Government launches national conversation on SEND

Government acts on commitment to make sure parents play a central role in helping shape the future Special Educational Needs and Disabilities (SEND) system, as it sets ambition to deliver the biggest national conversation on SEND in a generation. The government inherited a SEND system on its knees, with too many children let down and parents fighting just […]
Small businesses celebrated as PM brings high street to Downing Street for Christmas switch-on

PM hosts Christmas market-style showcase at Downing Street, celebrating small firms, frontline workers and community champions at the annual lights switch-on. Small businesses are set for a bumper festive season, with spending up 19% on last year – which could provide an extra £5 billion boost. Budget 2025 delivered key support, including extended Rates Relief, full funding for […]
Update on the Chair of the Office for Budget Responsibility (OBR)

Updates to this page Published 1 December 2025 Last updated 1 December 2025 + show all updates 1 December 2025 Chancellor letter added. 1 December 2025 First published. Source link